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The final word: Amazon鈥檚 healthcare strategy is advancing, with D2C telehealth and primary care now established and pharmacy sales growing (from $1.25 billion in 2023 to $1.8 billion in 2024, per Business Insider). The Health AI chatbot for search and medical advice could be the virtual consumer concierge to amplify engagement and increase sales.

The three telehealth companies will integrate with Novo鈥檚 new D2C online pharmacy, NovoCare, to complete medication orders. Zooming in: Novo鈥檚 tie-up with Hims is the most surprising piece of this news considering their public feud over Hims selling compounded semaglutide (Wegovy).

As linear TV viewership declines, live sports continue to drive engagement and brand loyalty, making them an attractive option for direct-to-consumer brands. Agencies are responding to demand. Publicis recently launched an initiative to streamline women鈥檚 sports ad buys.

Consumer packaged goods (CPG) brands have attempted to break into D2C ecommerce in recent years, to varying degrees of success. How can they avoid unprofitable strategies and develop a viable D2C ecommerce channel?

D2C ecommerce will continue to grow at above-average rates. But that growth will be driven by established brands selling directly鈥攏ot digitally native brands.

New healthcare and pharma D2C business ventures will emerge in 2025. They鈥檒l join a cohort of established and nontraditional industry players that have recently entered the D2C healthcare market. The new model aims to reach more customers while generating revenues through an alternative sales channel. Some examples of the sector鈥檚 D2C push include:. Drug developers, including Eli Lilly and Pfizer.

A ban on D2C pharmaceutical ads could become a reality during President Trump鈥檚 second term. It would be well received by the public: Adults are more than twice as likely to support (59%) a ban on prescription drug TV ads as they are to oppose one (25%), per a December 2024 Axios-Ipsos poll.

The company added 6.4 million streaming subscribers, increased direct-to-consumer (DTC) profits, and posted a deeper $494 million net loss. Studio revenues grew 15% as WBD restructured to address linear TV challenges. By the numbers:. Global Max and Discovery+ subscribers: 116.9 million, up 6.4 million in Q4. WBD projects 150 million streaming subscribers by the end of 2026.

The initiative includes a Nike shop-in-shop concept, reflecting Nike's ongoing pivot away from its direct-to-consumer push of recent years. The rotating concept is designed to drive repeat visits as featured brands change. "It's not just a clever name, it is going to rotate," said our analyst Zak Stambor. "Interesting to see them go with Nike first.

For a brand like Kettle & Fire, which began as direct-to-consumer before expanding into retail, the transition to retail media required developing frameworks for channel prioritization and budget allocation. Niccol貌 Gloazzo, senior director of media and omnichannel at Kettle & Fire, recommends starting at the bottom of the funnel first.

D2C ecommerce is rapidly evolving, driven by digital marketing, AI-enhanced personalization, sustainability, and more. By identifying and leveraging these emerging trends, businesses can effectively adapt to this competitive environment and address the dynamic expectations of consumers today.

As acquisition costs continue to rise, it鈥檚 crucial for D2C brands to double down on the value provided to customers. For outdoor lifestyle company Solo Brands, this meant putting its loyal fan base first by leaning into customer experience, communication, and its value proposition to keep customers engaged and coming back for more.

A presence on marketplaces, direct-to-consumer (D2C) channels, and social commerce platforms ensures you meet shoppers where they are. Enhance the digital shopping experience. "The retail landscape is more competitive than ever," said Perkins.

By the numbers: The significant brand heat On is generating is translating into higher D2C and full-price sales, which explains its sizable profit margins. D2C sales rose 43.4% YoY to account for 48.8% of Q4 net sales, another company record, bolstered by On鈥檚 growing store footprint.

Our take: This tie-up will be a large volume opportunity for Affirm鈥擲titch Fix鈥檚 direct-to-consumer (D2C) ecommerce sales will total $1.28 billion this year, according to our forecasts. It will help the BNPL player keep growing its GMV, which shot up 35% YoY in its most recent quarter.

On Running is firing on all cylinders: The performance footwear company grew D2C and wholesale revenues鈥攁s well as market share鈥攊n Q2.

Connected TV (CTV)鈥檚 digital DNA and ability to target specific audiences has catapulted its popularity among advertisers. Learn why a wide variety of advertisers, including direct-to-consumer brands, are using CTV ads to reach streaming viewers and drive measurable results.

List prices of the drugs hover around $1,000 per month, although both offer cash-pay discounts: NovoCare Pharmacy charges $499 for Wegovy while LillyDirect鈥檚 D2C ranges from $349 to $599 for Zepbound. Why it matters: Commercial insurance coverage for GLP-1s is dropping, and the current administration does not support expanding gov鈥檛 plans to cover the meds for obesity.

The next phase of direct-to-consumer (D2C) retail won鈥檛 be defined by a singular distribution strategy, but rather by the goal of making a real connection with customers. To get to the next level, D2Cs must use their physical presence, partnerships, marketing dollars, and customer data.

D2C brands facing the declining effectiveness of search and social ads must use new strategies outside of the traditional D2C growth playbook.

Digitally native brands look for a new D2C playbook: Brands are embracing wholesale, physical retail, acquisitions, and even selling on Amazon to regain momentum and achieve profitability.

Walmart to sell Bonobos as digitally native D2C brands lose their luster: WHP Global and Express will acquire the brand for $75 million to shore up the latter鈥檚 business.

As Facebook loses relevance with younger audiences, D2C ad budgets for CPG brands are diversifying into emerging channels.

Digital D2C disruptors, like Peloton and Casper, will bring in about $100 billion less in US ecommerce sales than the $134.55 billion of their established counterparts this year, according to our forecast.