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The 15 biggest US ecommerce players aren鈥檛 a surprise (here鈥檚 looking at you, Amazon, Walmart, and Apple). User-friendly mobile apps, quick delivery, innovation, and converting sales are what turn retailers into ecommerce powerhouses. Here are the companies our analysts believe best exemplify those features within the 15 largest ecommerce players.

The news: Spirit Halloween canceled its annual kickoff event due to 鈥渋nternational disruptions and supply chain challenges,鈥� it said in a social media post. Our take: While the retailer did not directly cite tariffs, it is the latest warning sign that President Donald Trump鈥檚 鈥淟iberation Day鈥� duties could result in emptier shelves during key shopping seasons.

The news: President Donald Trump鈥檚 immigration crackdown is chilling consumer spending and reducing the available labor force for key industries like construction and hospitality. Our take: The US economy depends heavily on immigrants, both documented or otherwise. The Trump administration鈥檚 aggressive deportation push could therefore deprive companies of crucial workers鈥攁nd drive up costs for essentials like housing and groceries鈥攁s well as eliminate a considerable source of tax revenues and consumer spending.

The trend: A perfect macroeconomic storm is causing younger consumers to cut back on spending. Our take: These pressures aren鈥檛 going away anytime soon. The Trump administration鈥檚 tariffs are leading retailers like Walmart, Best Buy, and Macy鈥檚 to raise prices鈥攑utting even more strain on young shoppers already feeling stretched. At the same time, job anxieties are growing. The white collar workforce is shrinking, and more companies are citing AI as a reason for layoffs. Put it all together, and it鈥檚 likely that younger consumers will remain cautious with their spending for some time, especially on nonessentials. Retailers that want to win over this group will need to focus on offering value such as high-quality, private label products.

The news: GoodRx is rolling out a subscription service for erectile dysfunction (ED) treatment. Our take: GoodRx is in a great position to compete with the top D2C telehealth players since consumers are already on the site or app searching for prescription drug discounts鈥攊t has over 6 million active monthly consumers who use a coupon code. GoodRx might also be more trusted than pure-play telehealth companies in the eyes of consumers since its services help people save money on their healthcare.

The trend: The Centers for Disease Control and Prevention (CDC) has lagged on delivering clear and coordinated messaging in recent weeks, creating confusion among consumers, physicians, and drugmakers. Our take: Inconsistency in messaging could result in patients, doctors, and healthcare entities not knowing where to turn for guidance and recommendations. Pharma companies should consider boosting consumer health messaging and offer healthcare providers鈥� science-based materials.

The payment services company hopes to win audiences connected to key international demographics.

The fintech company implements globally conscious strategies under economic volatility and new political tailwinds.

23andMe files for bankruptcy: A sale could give the acquiring company access to 15 million people鈥檚 genetic data. 23andMe鈥檚 downfall is a reminder of the risks when tech companies collect sensitive health data and struggle to sufficiently protect it.

Est茅e Lauder partners with India鈥檚 government to boost local beauty brands: The company is the latest to invest in the country as interest in premium beauty soars.

Prada nears 鈧�1.5 billion deal to acquire Versace: The move would give the luxury company broader appeal as spending cools.

Tech giants dominate Hollywood by securing marquee franchises: Companies like Amazon, Apple, and Netflix will outbid legacy media for top intellectual properties.

List of potential TikTok buyers grows while ban looms: The platform is drawing interest from new parties who could keep the key marketing channel afloat for millions of US companies.

Nearly every major retailer (and many smaller ones) has already launched media networks, but it鈥檚 not just for retailers anymore. While networks beyond retail have already begun to launch, 2025 will see more financial institutions, payment networks, travel companies, fitness centers, and more launch or revamp their own media networks. And as commerce media expands, so do the places ads are being served.

Tariffs on Chinese goods could hurt Google, Meta: Chinese retailers Temu and Shein are two of the 肠辞尘辫补苍颈别蝉鈥� top ad spenders.

The National Retail Federation鈥檚 (NRF) Big Show closed earlier this week, bringing together retailers, tech companies, and industry experts to discuss the future of retail. Key takeaways included Gen Z鈥檚 influence on shopping, which will last even if TikTok goes away, the accelerating trend cycle, hesitation to adopt new payment technologies, and the transformation of digital grocery. Here are four takeaways from the event.

The divide between top-tier brands and the rest of the luxury industry is widening: Companies like Brunello Cucinelli are outpacing the market as wealthy shoppers spend freely.